Squamous cell skin cancer
Squamous-cell skin cancer, also known as cutaneous squamous-cell carcinoma (cSCC), is one of the main types of skin cancer along with basal cell cancer, and melanoma.[10] It usually presents as a hard lump with a scaly top but can also form an ulcer.[1] Onset is often over months.[4] Squamous-cell skin cancer is more likely to spread to distant areas than basal cell cancer.[11]
The greatest risk factor is high total exposure to ultraviolet radiation from the Sun.[2] Other risks include prior scars, chronic wounds, actinic keratosis, lighter skin, Bowen’s disease, arsenic exposure, radiation therapy, poor immune system function, previous basal cell carcinoma, and HPV infection.[2][12] Risk from UV radiation is related to total exposure, rather than early exposure.[13] Tanning beds are becoming another common source of ultraviolet radiation.[13] It begins from squamous cells found within the skin.[14] Diagnosis is often based on skin examination and confirmed by tissue biopsy.[2][3]
Decreasing exposure to ultraviolet radiation and the use of sunscreen appear to be effective methods of preventing squamous-cell skin cancer.[5][6] Treatment is typically by surgical removal.[2] This can be by simple excision if the cancer is small otherwise Mohs surgery is generally recommended.[2] Other options may include application of cold and radiation therapy.[7] In the cases in which distant spread has occurred chemotherapy or biologic therapy may be used.[7]
As of 2015, about 2.2 million people have cSCC at any given time.[8] It makes up about 20% of all skin cancer cases.[15] About 12% of males and 7% of females in the United States developed cSCC at some point in time.[2] While prognosis is usually good, if distant spread occurs five-year survival is ~34%.[4][5] In 2015 it resulted in about 51,900 deaths globally.[9] The usual age at diagnosis is around 66.[4] Following the successful treatment of one case of cSCC people are at high risk of developing further cases.[2]
Collierville
Collierville is a town in Shelby County, Tennessee, United States, and a suburb located in the Memphis metropolitan area. The town had a population of 43,965 at the 2010 census.[5]
Collierville is a town of large houses and considerable retail expansion. Smaller, older houses are still found in the heart of Collierville, mainly between Byhalia Road and Collierville-Arlington on the east and west and Shelton and Highway 72 on the north and south. Some industry, notably Pepsi and Carrier, still dots the areas located south of Poplar Avenue.
Collierville is home to the Avenue at Carriage Crossing, an 800,000+ sq ft shopping center which opened in October 2005. Baptist Hospital, Collierville, serves the medical needs of the town’s residents. Collierville will become part of the Interstate 69 highway plan integrating Bill Morris Parkway (SR 385) as Interstate 269, part of this USDOT project linking Canada and Mexico with the United States.
Collierville was chosen as one of Relocate-America’s Top 100 Places to Live in 2008.[6] In 2014, Collierville’s historic town square was ranked by Parade Magazine as the “Best Main Street” in America.[7]